Palladium catalysed sequential imine arylation/Suzuki–Miyaura coupling: synthesis of a-(biarylyl)benzylamines
| dc.contributor.author | Marques, Carolina S. | |
| dc.contributor.author | Locati, Abel | |
| dc.contributor.author | Prates Ramalho, J.P. | |
| dc.contributor.author | Burke, Anthony J. | |
| dc.date.accessioned | 2016-01-27T16:54:12Z | |
| dc.date.available | 2016-01-27T16:54:12Z | |
| dc.date.issued | 2015 | |
| dc.date.updated | 2016-01-20T10:43:00Z | |
| dc.description.abstract | report an innovative, high yielding one-pot sequential catalytic imine arylation/SuzukieMiyaura cross-coupling reaction, which converts suitably activated imine substrates to various biarylarylmethyl amine products using several commercial Pd catalysts. Many biarylarylmethyl amine molecules are biologically active. Insightful computational studies detail the mechanism of the imine arylation process. The sequence of reactions is likely to be dependent on the reaction conditions. | por |
| dc.identifier | 00404020 | en_US |
| dc.identifier.authoremail | nd | |
| dc.identifier.authoremail | nd | |
| dc.identifier.authoremail | nd | |
| dc.identifier.authoremail | nd | |
| dc.identifier.citation | Marques, Carolina S.; Locati, Abel; Prates Ramalho, J.P.; Burke, Anthony J.Palladium catalysed sequential imine arylation/Suzuki–Miyaura coupling: synthesis of a-(biarylyl)benzylamines, Tetrahedron, 71, 21, 3314-3324, 2015. | por |
| dc.identifier.uri | http://hdl.handle.net/10174/16941 | |
| dc.language.iso | por | por |
| dc.rights | restrictedAccess | por |
| dc.title | Palladium catalysed sequential imine arylation/Suzuki–Miyaura coupling: synthesis of a-(biarylyl)benzylamines | por |
| dc.type | article | por |