Spine-Ghost: A New Bioactive Cement for Vertebroplasty

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dc.contributor.authorVitale-Brovarone, Chiara
dc.contributor.authorPontirolli, Lucia
dc.contributor.authorNovajra, Giorgia
dc.contributor.authorTcacencu, Ion
dc.contributor.authorReis, Joana
dc.contributor.authorManca, Antonio
dc.contributor.editorGinebra, Maria-Pau Edgar B. Montufar and Roman A. Perez
dc.contributor.editorCanal, Cristina
dc.contributor.editorEspanhol, Montserrat
dc.contributor.editorMontufar, Edgar
dc.contributor.editorPerez, Roman
dc.date.accessioned2015-01-22T12:11:45Z
dc.date.available2015-01-22T12:11:45Z
dc.date.issued2015
dc.description.abstractAn innovative, resorbable and injectable composite cement (Spine-Ghost) to be used for augmentation and restoration of fractured vertebrae was developed. Type III α-calcium sulfate hemihydrate (CSH) was selected as the bioresorbable matrix, while spray-dried mesoporous bioactive particles (SD-MBP, composition 80/20% mol SiO2/CaO), were added to impart high bioactive properties to the cement; a glass-ceramic containing zirconia was chosen as a second dispersed phase, in order to increase the radiopacity of the material. After mixing with water, an injectable paste was obtained. The developed cement proved to be mechanically compatible with healthy cancellous bone, resorbable and bioactive by soaking in simulated body fluid (SBF), cytocompatible through in-vitro cell cultures and it could be injected in ex-vivo sheep vertebra. Comparisons with a commercial control were carried out.por
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dc.identifier.authoremailjmfcr@uevora.pt
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dc.identifier.citationVitale-Brovarone, C, Pontirolli L, Novajra, G, Tcacencu, I, Reis, J & Manca, A (2015): Spine-Ghost: a new bioactive Cement for Vertebroplasty. Key Engineering Materials 631 (26): 43-47.por
dc.identifier.scientificarea458por
dc.identifier.urihttp://www.scientific.net/KEM.631.43
dc.identifier.urihttp://hdl.handle.net/10174/12492
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherKey Engineering Materialspor
dc.rightsopenAccesspor
dc.subjectvertebroplastypor
dc.subjectresorbable cementpor
dc.subjectmesoporous bioactive glasspor
dc.subjectspray-dryingpor
dc.titleSpine-Ghost: A New Bioactive Cement for Vertebroplastypor
dc.typearticlepor

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