BorArAm - Catalytic Asymmetric Arylating Cyclizations: A New Route to Chiral Bicyclic Amines

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dc.contributor.authorMendes, Paulo J.
dc.contributor.authorViana, H.
dc.contributor.authorMarques, C. S.
dc.contributor.authorBurke, Anthony J.
dc.date.accessioned2013-10-14T11:43:01Z
dc.date.available2013-10-14T11:43:01Z
dc.date.issued2013
dc.description.abstractNowadays neurodegenerative diseases such as Alzheimer’s disease and Parkinson disease represent a worldwide health threat. Rasagiline is one well-known medication for the treatment of Parkinson's disease, but more and cheaper alternatives are required.1 For this reason, our group is currently investigating a new catalytic asymmetric arylating2 cyclization route - borylation-arylation-amination (BorArAm) (Scheme 1) giving useful potential lead compounds based on the rasagiline core structure for treating these diseases. Our results will be discussed in this communication.por
dc.identifier.authoremailpjgm@uevora.pt
dc.identifier.authoremailnd
dc.identifier.authoremailnd
dc.identifier.authoremailnd
dc.identifier.citationH. Viana, C. S. Marques, Paulo J. Mendes, Anthony J. Burke, “BorArAm - Catalytic Asymmetric Arylating Cyclizations: A New Route to Chiral Bicyclic Amines”, 10º Encontro Nacional de Química Orgânica, 1º Simpósio Luso-Brasileiro de Química Orgânica, September 4-6, 2013, Lisbon, Portugal, Book of Abstracts PC103por
dc.identifier.scientificarea307por
dc.identifier.sharewithQUIpor
dc.identifier.urihttp://10enqo.eventos.chemistry.pt/?ver=sprogram
dc.identifier.urihttp://hdl.handle.net/10174/8856
dc.identifier.withinvitedoralpresentationnaopor
dc.identifier.withoralpresentationnaopor
dc.identifier.withpostersimpor
dc.language.isoengpor
dc.publisherSociedade Portuguesa de Químicapor
dc.rightsopenAccesspor
dc.subjectAsymmetric Catalysispor
dc.subjectBicyclic Aminespor
dc.titleBorArAm - Catalytic Asymmetric Arylating Cyclizations: A New Route to Chiral Bicyclic Aminespor
dc.typelecturepor
degois.publication.title10º Encontro Nacional de Química Orgânica, 1º Simpósio Luso-Brasileiro de Química Orgânica Book of Abstractspor

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