Ability to scavenge free radicals by Malus domestica Borkh. pulp reversed the stress profile induced by vanadium (V) in Saccharomyces cerevisiae,

Abstract

Functional value and the antioxidant properties of food are considered nowadays a very important feature for human consumption. In the literature apple is considered to have prophylactic and therapeutic properties in several human pathologies in part due to its content in phenols. So, the aim of this work was to determine how aqueous extract of apple pulp, collected at different times of the harvest period, affect the antioxidant response of Saccharomyces cerevisiae BY4741 expoused to vanadium pentoxide (2 mM). The results reveal a stabilization of the redox status by glutathione thet seems strongly consolidated by the presence of the fruity extract and deficit in glutathione peroxidase and catalase T activities induced by the presence of vanadium in culture medium contributed to the increase of ROS and loss of cell viability. However, the presence of apple extract rich in polyphenols and with great antioxidant reversed the response profile of S. cerevisiae to vanadium pentoxide.